Date Name Title Filing Type Shares Traded Price Total Held
Apr 23, 2007
SVP, Research & Devel Sciences
SVP, Research & Devel Sciences Form 4 Open market or private sale of non-derivative or derivative security 2,083 $25.65 5,077
Apr 23, 2007
SVP, Research & Devel Sciences
SVP, Research & Devel Sciences Form 4 Open market or private sale of non-derivative or derivative security 780 $25.75 4,297
Apr 20, 2007
SVP, Research & Devel Sciences
SVP, Research & Devel Sciences Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 25,000 $8.77 29,297
Apr 20, 2007
SVP, Research & Devel Sciences
SVP, Research & Devel Sciences Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 8,403 $26.09 20,894
Apr 20, 2007
SVP, Research & Devel Sciences
SVP, Research & Devel Sciences Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 5,609 $26.09 15,285
Apr 20, 2007
SVP, Research & Devel Sciences
SVP, Research & Devel Sciences Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 25,000 -- 25,000
Dec 18, 2006
SVP, Therap & Clin Prog Dev
SVP, Therap & Clin Prog Dev Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 4,921 -- 4,921
Dec 18, 2006
SVP, Therap & Clin Prog Dev
SVP, Therap & Clin Prog Dev Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 95,079 -- 95,079
Nov 01, 2006
SVP, Therap & Clin Prog Dev
SVP, Therap & Clin Prog Dev Form 4 Open market or private sale of non-derivative or derivative security 5,760 $20.00 3,887
Oct 31, 2006
SVP, Therap & Clin Prog Dev
SVP, Therap & Clin Prog Dev Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 18,311 $10.56 22,198

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.