Date Name Title Filing Type Shares Traded Price Total Held
Aug 05, 2022
EVP Research and Development
EVP Research and Development Form 4 Open market or private sale of non-derivative or derivative security 502 $619.64 53,072
Aug 05, 2022
EVP Research and Development
EVP Research and Development Form 4 Open market or private sale of non-derivative or derivative security 177 $620.11 52,895
Aug 05, 2022
EVP Research and Development
EVP Research and Development Form 4 Open market or private sale of non-derivative or derivative security 100 $621.11 52,795
Aug 04, 2022
EVP Research and Development
EVP Research and Development Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 95,000 $270.43 147,795
Aug 04, 2022
EVP Research and Development
EVP Research and Development Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 71,218 $613.00 76,577
Aug 04, 2022
EVP Research and Development
EVP Research and Development Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 95,000 -- --
Feb 18, 2022
EVP Research and Development
EVP Research and Development Form 4 Bona fide gift 335 -- 52,795
Dec 10, 2021
EVP Research and Development
EVP Research and Development Form 4 Other acquisition or disposition -- -- 5,792
Dec 10, 2021
EVP Research and Development
EVP Research and Development Form 4 Other acquisition or disposition -- -- 4,605
Dec 08, 2021
EVP Research and Development
EVP Research and Development Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 2,926 -- 53,883

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.