Date Name Title Filing Type Shares Traded Price Total Held
Dec 08, 2021
EVP Research and Development
EVP Research and Development Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 12,494 -- 12,494
May 18, 2021
EVP Research and Development
EVP Research and Development Form 4 Other acquisition or disposition -- -- 5,787
May 18, 2021
EVP Research and Development
EVP Research and Development Form 4 Other acquisition or disposition -- -- 9,134
May 17, 2021
EVP Research and Development
EVP Research and Development Form 4 Open market or private sale of non-derivative or derivative security 3,379 $518.63 38,422
May 17, 2021
EVP Research and Development
EVP Research and Development Form 4 Open market or private sale of non-derivative or derivative security 10,336 $519.47 28,086
May 17, 2021
EVP Research and Development
EVP Research and Development Form 4 Open market or private sale of non-derivative or derivative security 3,806 $520.17 24,280
May 14, 2021
EVP Research and Development
EVP Research and Development Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 40,000 $179.13 64,280
May 14, 2021
EVP Research and Development
EVP Research and Development Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 27,775 $516.69 36,505
May 14, 2021
EVP Research and Development
EVP Research and Development Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 12,500 $52.03 49,005
May 14, 2021
EVP Research and Development
EVP Research and Development Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 7,204 $516.69 41,801

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.