Date Name Title Filing Type Shares Traded Price Total Held
Dec 15, 2004
SVP, Manuf & Process Sciences
SVP, Manuf & Process Sciences Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 64,463 -- 64,463
Dec 15, 2004
Director, Chief Exec Officer & President, Ten Percent Owner
Director, Chief Exec Officer & President, Ten Percent Owner Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 31,611 -- 31,611
Dec 15, 2004
Director, Chief Exec Officer & President, Ten Percent Owner
Director, Chief Exec Officer & President, Ten Percent Owner Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 218,389 -- 218,389
Dec 15, 2004
SVP, PreclinDevel & Biomol Sci
SVP, PreclinDevel & Biomol Sci Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 10,537 -- 10,537
Dec 15, 2004
SVP, PreclinDevel & Biomol Sci
SVP, PreclinDevel & Biomol Sci Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 89,463 -- 89,463
Dec 15, 2004
Director
Director Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 42,148 -- 42,148
Dec 15, 2004
Director
Director Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 270,352 -- 270,352
Dec 15, 2004
Director, EVP, CSO, & Pres Regn Res Labs
Director, EVP, CSO, & Pres Regn Res Labs Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 10,537 -- 10,537
Dec 15, 2004
Director, EVP, CSO, & Pres Regn Res Labs
Director, EVP, CSO, & Pres Regn Res Labs Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 189,463 -- 189,463
Oct 15, 2004
SVP, Manuf & Process Sciences
SVP, Manuf & Process Sciences Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 10,000 $4.25 21,391

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.