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Insider Transactions

Date Name Title Filing Type Shares Traded Price Total Held
Mar 09, 2020
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 78,376 $476.42 635,614
Feb 28, 2020
EVP Research and Development
EVP Research and Development Form 4 Other acquisition or disposition -- -- 5,736
Feb 28, 2020
EVP Research and Development
EVP Research and Development Form 4 Other acquisition or disposition -- -- 7,831
Feb 28, 2020
EVP Research and Development
EVP Research and Development Form 4 Other acquisition or disposition -- -- 13,700
Feb 27, 2020
EVP Research and Development
EVP Research and Development Form 4 Open market or private sale of non-derivative or derivative security 209 $435.93 21,520
Feb 27, 2020
EVP Research and Development
EVP Research and Development Form 4 Open market or private sale of non-derivative or derivative security 348 $436.43 21,172
Feb 27, 2020
EVP Research and Development
EVP Research and Development Form 4 Open market or private sale of non-derivative or derivative security 480 $437.41 20,692
Feb 27, 2020
EVP Research and Development
EVP Research and Development Form 4 Open market or private sale of non-derivative or derivative security 256 $438.63 20,436
Feb 27, 2020
EVP Research and Development
EVP Research and Development Form 4 Open market or private sale of non-derivative or derivative security 231 $439.73 20,205
Feb 27, 2020
EVP Research and Development
EVP Research and Development Form 4 Open market or private sale of non-derivative or derivative security 395 $440.24 19,810

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.

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